High Sensitivity Flow Cell for UHPLC/ECD


  • Adjustable Spacer Technology (AST)
  • No spacers or gaskets
  • Fast stabilization
  • Adapter-kit for Coulochem II & III

The SenCell™ is a new generation electrochemical flow cell specifically designed for highest sensitivity. The tool free assembly and the continuously adjustable working volume guarantee ease of use and fast  stabilization. The volume of the cell is small and can be adjusted between roughtly 0 and 300 nL. In addition, the cell can withstand a pressure of several bars, making the cell ideally suited for use in (U)HPLC with Electrochemical Detection (ECD).

Highest sensitivity

To realize the highest detection sensitivity, the cell design is based on the confined wall-jet principle. A three-electrode configuration is used consisting of working electrode (WE), reference electrode (REF) and auxiliary electrode (AUX). The AUX is kept at precisely the same potential as the reference electrode via a voltage clamp, compensating for any polarization effects that might occur at the electrodes. In addition, utmost care has been devoted to the quality and finishing of the electrode material so that the highest sensitivity with fast stabilization is achieved, making the cell ideally suited for ultra-trace analysis in (U)HPLC, micro- and capillary LC/ECD.

Adjustable Spacer Technology – AST[1]

The new design is using Adjustable Spacer Technology (AST), the use of polymeric gaskets (spacers) is now obsolete. The AST is a build-in micropositioner for the working electrode relative to the inlet. To adjust the electrode position simply turn the micropositioner mechanism in the cell with an adjustment key (which is provided). By minimizing the electrode distance (‘spacer’), more signal will be ‘squeezed out’. For many applications this will improve the detection sensitivity.

[1] Patent pending

Adjustment from position 2 to 1:  turn counter clockwise with the provided adjustment key. Adjustment of the SenCell from position 3 to 0.5 results in a 2,5 fold increase in signal.

Reference electrodes

The SenCell is available with 3 different color coded reference electrodes that can be easily exchanged to fit any application.

  • HyREF (Pd/H2) – black
  • ISAAC (In-Situ Ag/AgCl) – green
  • Salt Bridge (Ag/AgCl) – blue

Ease of use

The tool free, easy-lock screw assembly allows for fast (dis-)assembly. Furthermore the AST guarantees for highest sensitivity (S/N) and fast stabilization.

Adapter-kit for use with Coulochem II and III

Boost the sensitivity of your existing Coulochem detector (ESA) by making use of Antec’s SenCell. For easy installation an adapter-kit is available consisting of Faraday cage and appropriate cell cable, for more details, see Ordering Information


Faraday cage (open & close) for optimal shielding of SenCell used with Coulochem (ESA/Dionex) detector.