Model 2300

  • Unique Touch Panel, control via keys behind molded front panel
  • Easy to Use, Fast Start-up, No Consumable Parts, Low Cost of Operation
  • Designed for Rapid Resolution and Ultra Performance LC Systems
  • Controlled by PC Based Application via USB
  • Superior HPLC Detection to Replace or Complement your Current Detection
  • Precise Vapor Phase Control with SofTA Exclusive Thermo-Split™ Technology
  • Low Temperature Operation with Organic and Aqueous Mobile Phases
  • Sensitive Detection for a Wide Variety of Chemical Classes and Structures.


The SofTA Model 2300 ELS detector is ideal for any advanced research laboratory requiring high sensitivity, high flow rates, or analysis of semi-volatile compounds. They provide both heating and sub-ambient cooling of the Thermo-Split chamber for superior ELS detection. Two filter algorithms allow for adapting the instrument to either conventional or fast liquid chromatography. With 3+ orders of magnitude dynamic range, these detectors allow a user to quantify an analyte and still see an impurity. Because these detectors are oriented toward a research environment where a wide variety of analytical methods may exist, they can store and recall 10 different instrument profiles. Profiles (methods) can be created to optimize for commonly encountered HPLC conditions and analytes, then reloaded with a few keystrokes. During start-up, the ELS detector performs an extensive series of diagnostic checks, ensuring instrument functionality. And unlike ELS detectors from other manufacturers, internal temperatures are controlled from the nebulizer all the way to the exhaust tube. As a result, fluctuations in laboratory temperature during the course of a day, or from season to season, have negligible effect.

The Model 2300 is designed for use with Rapid Resolution and Ultra Performance LC Systems. They maintain the peak widths obtained with these systems. These are our fastest ELS detectors, with peak widths less than 1 second. The narrow peak widths provide for the extremely high sample throughput required in today’s laboratories. Narrow peaks also result in improved signal to noise, making these detectors about two times more sensitive than our other models.

These detectors also feature dual gas operation. Low-cost nitrogen is used as the nebulization and carrier gas for non-volatile and high to moderately low concentrations of semi-volatile analytes. Substituting helium provides maximum low-nanogram sensitivity for compounds with significant volatility by allowing ambient evaporation of the mobile phase.

The SofTA ELS detector nebulizer and spray chamber design provides gradient stabilitywithout gas flow control. The response of other ELS detectors is dependent on the viscosity of the mobile phase solvents. In other manufacturers’ ELS detector designs, low viscosity, organic mobile phases produce a greater number of droplets during nebulization when compared to higher viscosity aqueous mobile phases. SofTA ELS detectors do not respond significantly to solvent changes during the gradient.

The Model 2300 is designed to be placed beside the system. It can be configured to sit to the left or the right of the system. The narrow width of the detector, 6.5”, preserves valuable bench space. The attractive design of the detector is practical and durable. The hard anodized finish and laser marked labeling are solvent- and wear-resistant. The detector is controlled via the unique touch panel on the molded front or via the SofTA PC-based control application.

Superior Performance — SofTA exclusive technology provides

  • Very Low Detection Limits (5ng)
  • Enhanced Dynamic Range (up to 0.25mg or 3+ orders of magnitude)
  • Outstanding Reproducibility (~3%RSD)
  • Very Narrow Peak Widths (1sec)
  • Low Evaporation Temperatures (3mL/min water at 10°C SP/40°C DT)
  • No Baseline Shift with Extreme Gradients (0 –100% in 10 min)