ROXY EC for MS

ROXY EC for MS

ROXY EC/MS

Dedicated Electrochemistry system for EC/MS

 

  • Single compound conversion (oxidation/reduction)
  • Direct on-line EC/MS, without chromatography (LC)
  • All parts supplied for immediate installation and use
  • Fast metabolite profiling Phase 1 and 2 metabolism
  • Huge time and cost savings

 

 

The ROXY™ EC is the ideal introduction system for Electrospray Ionization (ESI)-MS for single compound conversion. For known compounds (e.g., drug candidates, pollutants, pesticides, etc) a quick profiling and/or reconfirmation of potential metabolites is often sufficient for decision making. Therefore, target compounds can be directly infused through the electrochemical ReactorCell™ into the MS, often without the need of any liquid chromatographic separation (HPLC), making EC/MS a very powerful tool for fast metabolic profiling and related applications.

The resulting time and cost savings are substantial when compared with daunting in vivo or in vitro experiments. The ROXY™ EC System is supplied with a dual syringe infusion pump and all connecting tubing and parts for immediate installation and use.

 

Brochures

  • 2014 – Productflyer ROXY

Notebook

Manuals

Posters

  • 221_070_01 – Online EC MS A Powerful Tool for Fast Prediction of Phase I and II Drug Metabolism
  • 221_076_01 – Expanding Role of Electrochemistry Mass Spectrometry in Life Sciences
  • 221_077_01 – Novel method for efficient reduction of disulfide bonds in peptides and proteins prior MS detection
  • 221_078_01 – Identification of electrochemically synthesized metabolites
  • 221_079_01 – Insights into Nucleic Acids Oxidation by ElectrochemistryLiquid ChromatographyMass Spectrometry
  • 221_090_01 – Degradation of Xenobiotics and Binding to Organic Matter by OnLine EC MS
  • 221_105_01 – Controlled Reduction of Disulfide Bonds in Biopharmaceuticals Using an Electrochemical Reactor Cell online with LCMS Rolduc 2014
  • 221_106_01 – ElectrochemistryMS a Powerful Tool in Drug Metabolism Rolduc 2014
  • 221_107_01 – ElectrochemistryMS a Powerful Tool in Drug Metabolism ASMS 2014
  • 221_108_01 – Controlled Reduction of Disulfide Bonds in Proteins and Peptides Using an Electrochemical Reactor Cell in online LCECMS ASMS 2014
  • 221_115_01 – Controlled Reduction of Disulfide Bonds in Biopharmaceuticals ElCheMS2015
  • 221_116_01 – Enhanced Pharmaceutical Stability ElCheMS2015
  • 221_117_01 – Mimicking Drug Metabolism ElCheMS2015
  • 221_118_01 – Electrochem Reduction of Disulfide Bonds ASMS2015
  • 221_120_01 – ECHDX for the Analysis of Protein Therapeutics HOS2015